{"id":8879,"date":"2022-07-19T14:22:34","date_gmt":"2022-07-19T07:22:34","guid":{"rendered":"https:\/\/chemistry.sc.mahidol.ac.th\/?page_id=8879"},"modified":"2022-07-21T13:52:04","modified_gmt":"2022-07-21T06:52:04","slug":"disposable-microchamber-with-a-microfluidic-paper-based-lid-for-generation-and-membrane-separation-of-so2-gas-employing-an-in-situ-electrochemical-gas-sensor-for-quantifying-sulfite-in-wine","status":"publish","type":"page","link":"https:\/\/chemistry.sc.mahidol.ac.th\/disposable-microchamber-with-a-microfluidic-paper-based-lid-for-generation-and-membrane-separation-of-so2-gas-employing-an-in-situ-electrochemical-gas-sensor-for-quantifying-sulfite-in-wine\/","title":{"rendered":"Disposable Microchamber with a Microfluidic Paper-Based Lid for Generation and Membrane Separation of SO2\u00a0Gas Employing an In\u00a0Situ Electrochemical Gas Sensor for Quantifying Sulfite in Wine"},"content":{"rendered":"\t\t
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This work presents a fully disposable microchamber for gas generation of a sample solution. The microchamber consists of a cylindrical well-reactor and a paper-based microfluidic lid (\u03bc<\/i>Fluidic lid), which also serves as the reagent loading and dispensing unit. The base of the reactor consists of a hydrophobic membrane covering an in-house graphene electrochemical gas sensor. Fabrication of the gas sensor and the three-layer \u03bc<\/i>Fluidic lid is described. The \u03bc<\/i>Fluidic lid is designed to provide a steady addition of the acid reagent into the sample solution instead of liquid drops from a disposable syringe. There are three steps in the procedure: (i) acidification of the sample in the reactor to generate SO2<\/sub>\u00a0gas by the slow dispensing of the acid reagent from the \u03bc<\/i>Fluidic lid, (ii) diffusion of the liberated SO2<\/sub>\u00a0gas through the hydrophobic membrane at the base of the reactor, and (iii) in situ detection of SO2<\/sub>\u00a0by cathodic reduction at the graphene electrode. The device was demonstrated for quantitation of the sulfite preservative in wine without heating or stirring. The selectivity of the analysis is ensured by the combination of the gas-diffusion membrane and the selectivity of the electrochemical sensor. The linear working range is 2\u201360 mg L\u20131<\/sup>\u00a0SO2<\/sub>, with a limit of detection (3SD of intercept\/slope) of 1.5 mg L\u20131<\/sup>\u00a0SO2<\/sub>. This in situ method has the shortest analysis time (8 min per sample) among all voltammetric methods that detect SO2(g)<\/sub>\u00a0via membrane gas diffusion.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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Reference:\u00a0 \u00a0<\/span><\/b>Prasertying, P.;<\/span>\u00a0 <\/span>Ninlapath, T.;<\/span>\u00a0 <\/span>Jantawong, N.;<\/span>\u00a0 <\/span>Wongpakdee, T.;<\/span>\u00a0 <\/span>Sonsa-ard, T.;<\/span>\u00a0 <\/span>Uraisin, K.;<\/span>\u00a0 <\/span>Saetear, P.;<\/span>\u00a0 <\/span>Wilairat, P.; Nacapricha, D., Disposable Microchamber with a Microfluidic Paper-Based Lid for Generation and Membrane Separation of SO2 Gas Employing an In\u00a0Situ Electrochemical Gas Sensor for Quantifying Sulfite in Wine. <\/span>Analytical Chemistry <\/i>2022,<\/b> 94<\/i> (22), 7892-7900.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

This work presents a fully disposable microchamber for gas generation of a sample solution. The microchamber consists of a cylindrical well-reactor and a paper-based microfluidic lid (\u03bcFluidic lid), which also serves as the reagent loading and dispensing unit. The base of the reactor consists of a hydrophobic membrane covering an in-house graphene electrochemical gas sensor. […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8879","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/pages\/8879","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/comments?post=8879"}],"version-history":[{"count":8,"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/pages\/8879\/revisions"}],"predecessor-version":[{"id":8957,"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/pages\/8879\/revisions\/8957"}],"wp:attachment":[{"href":"https:\/\/chemistry.sc.mahidol.ac.th\/wp-json\/wp\/v2\/media?parent=8879"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}